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Volume 47, Issue 9, Pages 888-894 (September 2011)
Association of −308 TNF-α promoter polymorphism with clinical aggressiveness in patients with head and neck squamous cell carcinoma Gefter Thiago Batista Corrêa, Gabriela Alencar Bandeira, Bruna Gonçalves Cavalcanti, Carlos Alberto de Carvalho Fraga, Erivelton Pereira dos Santos, Thiago Fonseca Silva, Ricardo Santiago Gomez, André Luiz Sena Guimarães, Alfredo Maurício Batista De Paula Oral Oncology Volume 47, Issue 9, Pages (September 2011) DOI: /j.oraloncology Copyright © 2011 Elsevier Ltd Terms and Conditions
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Figure 1 Polyacrylamide gel electrophoresis for detection of (308 G/A) TNF-α polymorphism. Base pair ladder (100bp) (lane 1); PCR product without digestion=107bp (lane 2); genotype AA=107bp (lane 7); genotype G/A=107+87bp (lanes 3 and 4); genotype GG=87bp (lanes 5 and 6). Oral Oncology , DOI: ( /j.oraloncology ) Copyright © 2011 Elsevier Ltd Terms and Conditions
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Figure 2 Overall survival analysis in HNSCC patients after 1826days according to TNF-α allele and haplotype frequencies, tumour size, and cervical metastasis parameters. The difference between groups was evaluated by the log-rank test and the differences were statistically significant. Oral Oncology , DOI: ( /j.oraloncology ) Copyright © 2011 Elsevier Ltd Terms and Conditions
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