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Acute Posterior Multifocal Placoid Pigment Epitheliopathy

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Apresentação em tema: "Acute Posterior Multifocal Placoid Pigment Epitheliopathy"— Transcrição da apresentação:

1 Acute Posterior Multifocal Placoid Pigment Epitheliopathy
N moura-coelho, MD1, al bASÍLIO, MD1, b carvalho, MD1, f Pinto-ferreira, MD1,2 1 Ophthalmology Department, Centro Hospitalar Lisboa Central (CHLC, EPE) 2 HEAD of the Ocular Inflammation Section – Ophthalmology department CHCL 30ª EDICIÓN GEMU UVEÍTIS 2017 – REUNIÓN GRUPO ESPAÑOL DE ESTUDIO DE LAS UVEÍTIS E INFLAMACIÓN OCULAR MADRID – 24 FEBRERO 2017

2 Case Report 38 year-old female, Caucasian, otherwise healthy
Chronic, progressive worsening of visual acuity (OD > OS) Onset at age 27: “Recurrent episodes of uveitis, characterized by acute vision loss in both eyes” (sic) BCVA OD = logMAR + 1,0 BCVA OS = logMAR + 0,7 Slit-lamp biomicroscopy: bilateral posterior subcapsular cataract, no other changes in anterior segment examination

3 Case Report

4 Case Report

5 Case Report Negative infectious serologies and auto-immune antibodies
HLA-A2, HLA-B44 (HLA-B27 negative; HLA-B5 negative; HLA-B51 negative; HLA-B7 negative; HLA-DR2 not tested) Neuroimaging, Chest Imaging, Abdominal Imaging: no changes Bilateral, acute posterior multifocal placoid pigment epitheliopathy (APMPPE) in inactive stage, with extensive macular and foveal involvement In APMPPE, unfavourable visual outcome occurs in up to 25%, usually in patients with macular and foveal involvement


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