Inflamação Fases da Inflamação - Amplificação Edema PMNs Monocytes/Macrophages REPAIR (fibroblasts) Activity 1 2 3 DAYS
Inflamação Infarto agudo do miocárdio (<10 horas), Macro Acute MI, showing hemorrhage in the posterior (bottom of slide) LV.
Inflamação Infarto agudo do miocárdio/ IAM(<10 horas), Micro Micro H&E showing normal myocardium on left (with some evidence of hypertrophy), and early infarction on the right. Note the brick-red color and lack of nuclei. No inflammatory cells have yet appeared.
Inflamação IAM (24-72 horas), macro Further evolution of an MI, showing yellowish discoloration, due to infiltration by PMNs.
Inflamação IAM (24-72 horas), Micro H&E showing predominance of neutrophils and dead myocardium.
Inflamação IAM (24-72 horas), micro Hi power of same. Note poly-lobated nuclei, typical of PMNs. The myocardial cells are all necrotic, lacking nuclei.
Inflamação IAM (>72 hours) com Macrófagos Macrophages, recognizable by their large size, eccentric nuclei and clear cytoplasm, often containing lipid, nuclear debris, or hemosiderin pigment.
Inflamação Infarto remoto do miocárdio (> 6 semanas), Macro Old MI showing a mature, white, collagenous scar.
Inflamação Infarto remoto do miocárdio (> 6 semanas), fibrose (detalhe) Same as previous.
Inflamação Infarto remoto do miocárdio (> 6 semanas),, Micro Low power H&E of an old MI, showing mature collagenous scar, blending with normal cardiac muscle. Scar is not capable of rhythmic contraction. Cardiologists say that scarred myocardium is “hypokinetic”.
Inflamação Infarto remoto do miocárdio (> 6 semanas), Tricromio Whole mount, demonstrating collagen scar (blue-green on trichrome stain).